EST alignments suggest that [secret number]% of Arabidopsis thaliana genes are alternatively spliced
نویسنده
چکیده
Recent estimates of the frequency of alternative splicing in human genes, in conjunction with recent estimates of the number of genes in the human genome, have confirmed that alternative splicing plays a critical role in human genetic complexity. However, despite this recent interest in alternative splicing as a fundamental genetic mechanism, and despite numerous experimentally confirmed examples of alternative splicing in plants, no genome-wide studies have been performed to estimate the frequency of alternative splicing in any plant species. Here we present an estimate of the number of alternatively spliced genes in Arabidopsis thaliana, based on genomic alignments of approximately [very large number] EST sequences. After strict filtering to eliminate false-positives, we estimate that the total number of alternatively spliced genes in Arabidopsis is [top secret number], or about [top secret number] of the total gene number.
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